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Intravenous vitamin C ( IVC )in the treatment of allergies

During acute allergic inflammation and in allergy-related respiratory or skin infections, the production of reactive oxygen species (ROS) plays an important role. A targeted antioxidant intervention to counteract the increases in ROS can be achieved by Vitamin C (ascorbate) as one of the most effective antioxidants in human blood plasma for protection against oxidative stress.

Data from multicenter, prospective, observational documented the clinical effects of high-dose iv vitamin C in the treatment of patients with known respiratory or cutaneous allergies.

This observational study was conducted to investigate the change in disease-specific and nonspecific symptoms (fatigue, sleep disorders, depression, and lack of mental concentration) during adjuvant treatment with intravenous vitamin C in 71 patients with allergy-related respiratory or cutaneous indications.

The authors conclude that there is a reduction of oxidative stress and inflammation by vitamin C and Vitamin C can be beneficial in patients with allergic diseases. This provides evidence of the use of high-dose iv vitamin C in clinic practice for the treatment of respiratory and cutaneous allergic diseases.


Intravenous vitamin C in the treatment of allergies: an interim subgroup analysis of a long-term observational study Claudia Vollbracht et al .J Int Med Res